Successful treatment of Kasabach-Merritt syndrome with transarterial embolization and corticosteroids.

Shao-yi Zhou, Hai-bo Li, Yue-ming Mao, Pei-ying Liu, Jing Zhang

Department of Interventional Radiology and Vascular Anomalies, Guangzhou Women and Children's Medical Center, Guangzhou 510623, PR China.

Journal of pediatric surgery 2013 Mar

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Kasabach-Merritt syndrome (KMS) refers to the combination of large neonatal vascular tumors and thrombocytopenic coagulopathy. However, a standard treatment regimen for KMS has not yet been established. We report a case of a 6-week-old male infant with life-threatening KMS who was successfully treated with transarterial embolization and corticosteroids. One week after initiating the corticosteroid treatment, his platelet counts recovered, and the lesion growth halted. The approach with corticosteroid therapy resulted in an excellent response that was maintained long enough for us to perform transarterial embolization therapy. The combination of transarterial embolization and corticosteroid therapy should be considered as an option for Kasabach-Merritt syndrome. Copyright © 2013 Elsevier Inc. All rights reserved.

Citation

Shao-yi Zhou, Hai-bo Li, Yue-ming Mao, Pei-ying Liu, Jing Zhang. Successful treatment of Kasabach-Merritt syndrome with transarterial embolization and corticosteroids. Journal of pediatric surgery. 2013 Mar;48(3):673-6