Rapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus.

Marc Mendelson, Zunaid Barday, Roland Eastman, David Le Feuvre, Sally Candy, Hue-Tsi Wu, Charles Swanepoel

Department of Medicine, Groote Schuur Hospital, Cape Town, South Africa. marc.mendelson@uct.ac.za

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2012 Dec

filter terms:

Sirolimus, a potent inhibitor of B- and T-cell activation. is a commonly used immunosuppressant after renal transplantation. Withdrawal of sirolimus from the immunosuppression regimen may reduce B-cell surveillance. We present a case of rapidly progressive central nervous system (CNS) polymorphic Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder following the withdrawal of sirolimus.

Citation

Marc Mendelson, Zunaid Barday, Roland Eastman, David Le Feuvre, Sally Candy, Hue-Tsi Wu, Charles Swanepoel. Rapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2012 Dec;102(12):924-6