Progress on materials and scaffold fabrications applied to esophageal tissue engineering.

Qiuxiang Shen, Peina Shi, Mongna Gao, Xuechan Yu, Yuxin Liu, Ling Luo, Yabin Zhu

School of Medicine, Ningbo University, Ningbo 315211, China.

Materials science & engineering. C, Materials for biological applications 2013 May 1

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The mortality rate from esophageal disease like atresia, carcinoma, tracheoesophageal fistula, etc. is increasing rapidly all over the world. Traditional therapies such as surgery, radiotherapy or chemotherapy have been met with very limited success resulting in reduced survival rate and quality of patients' life. Tissue-engineered esophagus, a novel substitute possessing structure and function similar to native tissue, is believed to be an effective therapy and a promising replacement in the future. However, research on esophageal tissue engineering is still at an early stage. Considerable research has been focused on developing ideal scaffolds with optimal materials and methods of fabrication. This article gives a review of materials and scaffold fabrications currently applied in esophageal tissue engineering research. Copyright © 2013 Elsevier B.V. All rights reserved.

Citation

Qiuxiang Shen, Peina Shi, Mongna Gao, Xuechan Yu, Yuxin Liu, Ling Luo, Yabin Zhu. Progress on materials and scaffold fabrications applied to esophageal tissue engineering. Materials science & engineering. C, Materials for biological applications. 2013 May 1;33(4):1860-6