Ways in which SWL affects oxidant/antioxidant balance.

Many damages can occur in the kidneys following extracorporeal shock wave lithotripsy (SWL) and some of these damages are thought to emerge as a result of oxidative stress. The objective of this study is to evaluate the impact of SWL application on kidneys in stone patients on oxidative stress parameters in 24-h urine. The study included 20 patients scheduled for SWL. total antioxidant capacity (TAC) and total oxidant status (TOS) measurements were made on 24-h urines of the patients before and after SWL. The oxidative stress index (OSI) was calculated based on these values. Following SWL, while TOS increased in 24-h urine (p = 0.006), TAC remained unchanged (p = 0.312). OSI increased following the procedure (p = 0.004). SWL application disrupts the oxidant/antioxidant balance in favor of oxidants, which leads to oxidative stress. TOS, TAC and OSI may be useful in the determination of the existence of oxidative stress following SWL.

Citation

Erdal Yilmaz, Ahmet Haciislamoglu, Ucler Kisa, Ozlem Dogan, Ercan Yuvanc, Ertan Batislam. Ways in which SWL affects oxidant/antioxidant balance. Urolithiasis. 2013 Apr;41(2):137-41

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PMID: 23503875

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