Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

In this article the importance of blood proteins for drug dosing regimes is discussed. A simple mathematical model is presented for estimating recommended drug doses when the concentration of blood proteins is decreased. Practical guidance for drug dosing regimes is discussed and given in the form of a figure. It is demonstrated that correction of drug dosing regimes is needed only for when there is a high level of drug conjugation with blood proteins and a high degree of hypoalbuminaemia. An example of the use of this model is given.


Konstantin G Gurevich. Effect of blood protein concentrations on drug-dosing regimes: practical guidance. Theoretical biology & medical modelling. 2013 Mar 18;10:20

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 23506635

View Full Text