A case of seronegative catastrophic antiphospholipid antibody syndrome.

Stamford Hospital/Columbia University, College of Physicians and Surgeons, 30 Shelburne Road, Stamford, CT 06904, USA.

Connecticut medicine 2013 Feb

Catastrophic antiphospholipid antibody syndrome (CAPS) is a rare syndrome associated with multiorgan failure that carries a high mortality rate. It has been defined previously by the presence of autoantibodies in a patient with acute multiorgan failure as a result of small vessel occlusion by multiple thrombi. We report a patient who meets all criteria of CAPS except for persistent seronegativity.