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Musculoskeletal manifestations in chronic renal insufficiency are caused by complex bone metabolism alterations, now described under the umbrella term of chronic kidney disease mineral- and bone-related disorder (CKD-MBD), as well as iatrogenic processes related to renal replacement treatment. Radiological imaging remains the mainstay of disease assessment. This review aims to illustrate the radiological features of CKD-MBD, such as secondary hyperparathyroidism, osteomalacia, adynamic bone disease, soft-tissue calcifications; as well as features associated with renal replacement therapy, such as aluminium toxicity, secondary amyloidosis, destructive spondyloarthropathy, haemodialysis-related erosive arthropathy, tendon rupture, osteonecrosis, and infection. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.


C Y Lim, K O Ong. Various musculoskeletal manifestations of chronic renal insufficiency. Clinical radiology. 2013 Jul;68(7):e397-411

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PMID: 23522485

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