A sensitive SERS assay of L-histidine via a DNAzyme-activated target recycling cascade amplification strategy.

Sujuan Ye, Yuanyuan Guo, Jie Xiao, Shusheng Zhang

Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

Chemical communications (Cambridge, England) 2013 May 7

filter terms:

A novel surface-enhanced Raman scattering (SERS) method is demonstrated to detect L-histidine based on DNAzyme which can specifically recognize L-histidine. Through a target recycling cascade amplification strategy, the DNAzyme-based SERS sensing system affords very high sensitivity for L-histidine with a detection limit of 0.56 nM.

Citation

Sujuan Ye, Yuanyuan Guo, Jie Xiao, Shusheng Zhang. A sensitive SERS assay of L-histidine via a DNAzyme-activated target recycling cascade amplification strategy. Chemical communications (Cambridge, England). 2013 May 7;49(35):3643-5