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Advances in the treatment of pediatric and adult cancer have reduced the mortality rates from these disorders and have led to an ever-increasing population of long-term survivors. Chemotherapy and radiotherapy may cause premature cardiac disease that may be asymptomatic or symptomatic. All patients exposed to chemotherapy with cardiotoxic potential or chest radiotherapy have stage A heart failure and the goal of surveillance and treatment is to prevent progression to stages B-D. Screening strategies, including the use of biomarkers, echocardiography, and expert opinion surveillance and treatment recommendations, are presented. Copyright © 2013 Elsevier Inc. All rights reserved.


Joseph R Carver, Dava Szalda, Bonnie Ky. Asymptomatic cardiac toxicity in long-term cancer survivors: defining the population and recommendations for surveillance. Seminars in oncology. 2013 Apr;40(2):229-38

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PMID: 23540748

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