Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY.
Kayoko Esaki, Taketo Ohmori, Motohiro Maebuchi, Toshihiro Nakamori, Toshihisa Ohshima, Shigeki Furuya
Division of Systems Biology, Department of Innovative Science and Technology for Bio-industry, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan.
Bioscience, biotechnology, and biochemistry 2013We examined the effect of orally administering L-Ser-L-Tyr (SY) dipeptide on the brain of a serine deficiency disease model mouse to attain the efficient delivery of L-Tyr and L-Ser into the mouse brain. Oral SY administration increased the L-Tyr level more efficiently than L-Tyr administration with the same intake dose, but did not significantly affect the L-Ser level when compared with L-Ser administration.
Citation
Kayoko Esaki, Taketo Ohmori, Motohiro Maebuchi, Toshihiro Nakamori, Toshihisa Ohshima, Shigeki Furuya. Increased tyrosine in the brain and serum of mice by orally administering dipeptide SY. Bioscience, biotechnology, and biochemistry. 2013;77(4):847-9
PMID: 23563534
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