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In this issue of Blood, Janelsins et al report that substance P (SP)–treated dendritic cells (DCs) efficiently home to lymph nodes, where they induce inflammatory DCs to produce interleukin-12 (IL-12), thereby promoting type 1 polarized immunity.
Citation
Akira Takashima. Harnessing DCs by substance P. Blood. 2013 Apr 11;121(15):2815-6
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Substances
PMID: 23580632
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