Genetics and stressful life events interact in depression].

The aim of the present review was to present clinical aspects of recent research in genes, the experience of stressful life events and depression. 60-70% experience a moderate to severe stressful life event half a year prior to the first onset of depression, whereas later depressive episodes to a lesser extent are preceded by stressful life events. Clinical features do not differ between depressions with or without prior stressful life events. Certain genetic variations in the serotonin receptor system seem to increase the risk of developing depression in relation to experiencing stressful life events.

Citation

Lars Vedel Kessing, Jens Drachmann Bukh. Genetics and stressful life events interact in depression]. Ugeskrift for laeger. 2013 Apr 1;175(14):948-51

Mesh Tags

Substances

PMID: 23582067

search → result