Adipokines and coronary artery disease].

Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II, Italy.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 2012 Sep

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Adipose tissue, besides being an important energetic storage, is also a source of cytokines and hormones which act in a paracrine, autocrine and especially endocrine manner, influencing the cardiometabolic axis. Adipokines are a group of mediators with pleiotropic function, that are involved in many physiological processes, so that a disregulation in their secretion can lead to multiple pathological conditions. In this review our aim was to clarify the role of adipokines in the pathogenesis of atherosclerosis, especially in coronary artery disease, and based on current scientific evidence, to analyze the therapeutic and behavioral strategies that are so far available.

Citation

Teresa Strisciuglio, Gennaro Galasso, Dario Leosco, Roberta De Rosa, Giuseppe Di Gioia, Valentina Parisi, Stefania De Luca, Tullio Niglio, Chiara De Biase, Rossella Luciano, Giuseppe Rengo, Bruno Trimarco, Federico Piscione. Adipokines and coronary artery disease]. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo. 2012 Sep;78(3):120-8