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We detected 2 hepatitis E virus (HEV) strains in an acutely infected immunocompetent patient. Two populations of genotype 3 virus were observed in the hypervariable regions and open reading frames 2 and 3, indicating multiple infection with hepatitis E virus. Persons with mixed infections may provide the opportunity for virus recombination.

Citation

Donald B Smith, Jeff Vanek, Louise Wellington, Ingolfur Johannessen, Sandeep Ramalingam, Peter Simmonds. Hepatitis E virus mixed infection in immunocompetent patient. Emerging infectious diseases. 2013 Mar;19(3):468-70

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PMID: 23621890

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