Acute kidney injury in children: an update on diagnosis and treatment.

James D Fortenberry, Matthew L Paden, Stuart L Goldstein

Critical Care Division, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta at Egleston, Atlanta, GA 30322, USA. james.fortenberry@choa.org

Pediatric clinics of North America 2013 Jun

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The concept and definition of acute kidney injury (AKI) in adults and children has undergone significant change in recent years. Biomarker assessment is aiding in description, defining and understanding timing of AKI. AKI demonstrates unique characteristics in association with sepsis and septic shock, organ dysfunction, and fluid overload. Treatment remains problematic, but growing experience with pediatric continuous renal replacement therapies has improved the delivery of care in children. Increasingly, continuous renal replacement therapy is provided in combination with other extracorporeal technologies, and approaches are advancing to improve combined therapy use. Copyright © 2013 Elsevier Inc. All rights reserved.

Citation

James D Fortenberry, Matthew L Paden, Stuart L Goldstein. Acute kidney injury in children: an update on diagnosis and treatment. Pediatric clinics of North America. 2013 Jun;60(3):669-88