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A 48-year-old man was admitted to our hospital complaining of acute severe abdominal pain and constipation. He had received bone marrow transplantation for acute myelogenous leukemia 5 months previously and immunosuppressant treatment for chronic graft-versus-host disease. Abdominal X-ray and CT scan films revealed his large intestine widely dilated and filled with air, and colonic pseudo-obstruction was diagnosed. It was difficult to ascertain the cause of the symptoms until 6 days after onset of the abdominal pain when disseminated zoster eruption appeared over his whole body. It was disseminated varicella-zoster and complicated with colonic pseudo-obstruction. He was treated with acyclovir. It is important to suspect disseminated varicella-zoster and treat early immunocompromised patients complaining of severe acute abdominal pain and colonic pseudo-obstruction.

Citation

Emiko Tanida, Motoyoshi Izumi, Tsuyoshi Abe, Izumi Tsuchiya, Kanji Okuma, Eri Uchida, Akihisa Hidaka, Eri Hayashi, Masaaki Noguchi, Yoshifumi Masui, Kai Yoshizawa, Keigo Shirahama, Akira Kanezaki. Disseminated varicella-zoster virus infection complicated with severe abdominal pain and colonic pseudo-obstruction]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 2013 May;110(5):839-45

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PMID: 23648540

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