Influence of ethanol-metabolising systems on intensity of lipid peroxidation processes in gastrointestinal tract of rats].

N É Petushok, T Ch Grokhovskaia, N G Mel'nichenko, S P Pron'ko

Biomedit͡sinskai͡a khimii͡a 2013 Jan-Feb

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The effects of some ethanol-metabolising systems (aldehyde dehydrogenase, catalase, cytochrome P450 2E1) on activation of lipid peroxidation (LPO) processes in gastrointestinal tract of rats have been studied using inhibitors of these systems. The intensity of LPO processes was evaluated by thiobarbituric acid-reactive products and chemiluminiscence intensity. It was found, that the acetadehyde metabolism play the main role in the indiction of lipid peroxidation in the gastrointestinal tract of rats.

Citation

N É Petushok, T Ch Grokhovskaia, N G Mel'nichenko, S P Pron'ko. Influence of ethanol-metabolising systems on intensity of lipid peroxidation processes in gastrointestinal tract of rats]. Biomedit͡sinskai͡a khimii͡a. 2013 Jan-Feb;59(1):76-80