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Morphofunctional pecularities of the bone marrow neutrophil maturation were studied in the progeny of female rats with chronic experimental toxic hepatitis, similar to hepatitis B by morphological, biochemical, and physiological characteristics. The lysosomal, phagocytic, and killing activities of cells were reduced during the morphologically identifiable stages of neutrophilopoiesis (myeloblasts, promyelocytes, myelocytes, metamyelocytes, stab and segmented neutrophils).


G V Bryukhin, N V Nevzorova. Contribution of maternal chronic experimental hepatic disease to the development of nonspecific cell resistance in the progeny. Bulletin of experimental biology and medicine. 2013 May;155(1):104-7

PMID: 23667884

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