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Route to destruction: autophagosomes SNARE lysosomes.

Helmut Krämer

The Journal of cell biology 2013 May 13


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    Autophagy allows cells to encapsulate parts of their cytosol into unique double-membrane structures. These autophagosomes mature to fuse with lysosomes and deliver the enclosed contents for degradation. Three recent papers, including one by Takáts et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201211160), have taken different routes to discover a role for Syntaxin 17 in the maturation of autophagosomes.

    Citation

    Helmut Krämer. Route to destruction: autophagosomes SNARE lysosomes. The Journal of cell biology. 2013 May 13;201(4):495-7

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    PMID: 23671308

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