Interaction of dihydromyricetin and alpha-amylase.

Lei Chen, Chao Wang, Qingyi Wei, Zhengxiang Ning, Erdong Yuan

College of Light Industry and Food Science, South China University of Technology, Guangzhou 510640, PR China.

Natural product communications 2013 Mar

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The interaction of dihydromyricetin (DMY) and alpha-amylase was investigated. The complex formed between DMY and alpha-amylase resulted in decreased antioxidant activity of DMY and the catalytic activity of the enzyme, as well as efficient quenching of the intrinsic fluorescence of alpha-amylase. An alpha-amylase molecule provides one binding site for a DMY molecule. These results will be useful for exploiting this compound to combat diseases efficiently.

Citation

Lei Chen, Chao Wang, Qingyi Wei, Zhengxiang Ning, Erdong Yuan. Interaction of dihydromyricetin and alpha-amylase. Natural product communications. 2013 Mar;8(3):339-42