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In this issue of Blood, Jakob et al report that hematopoietic progenitor kinase 1 (HPK1) participates during signaling of neutrophil recruitment by acting as a regulator of the adhesiveness of the b2-integrin lymphocyte function-associated antigen 1 (LFA-1) during acute inflammation.
Citation
Scott I Simon. Gimme a brake: HPK1 regulates LFA-1 and neutrophil traction. Blood. 2013 May 16;121(20):4017-8
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PMID: 23682030
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