Myoclonic seizure due to cyclopentolate eye drop in a preterm infant.

Ayşe Büyükcam, H Tolga Celik, Ayşe Korkmaz, Murat Yurdakök

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. dr.aysebaktir@gmail.com

The Turkish journal of pediatrics 2012 Jul-Aug

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Cyclopentolate is widely used in ophthalmology for its intense mydriatic and cycloplegic activity. Systemic side effects have been described in both adults and children. Myoclonic seizure is a rare side effect of eye drops that are used in eye examinations. We report herein a case of convulsion in a three month- old girl following cyclopentolate hydrochloride and phenylephrine hydrochloride eye drops, which were used in advance of ophthalmoscopy for examination of retinopathy of prematurity (ROP). Physicians should be aware of the uncommon systemic side effects of cyclopentolate, and drops should be used in appropriate dosages.

Citation

Ayşe Büyükcam, H Tolga Celik, Ayşe Korkmaz, Murat Yurdakök. Myoclonic seizure due to cyclopentolate eye drop in a preterm infant. The Turkish journal of pediatrics. 2012 Jul-Aug;54(4):419-20