Drug-induced immune thrombocytopenia.

Thrombocytopenia is caused by immune reactions elicited by diverse drugs in clinical practice. The activity of the drug-dependent antibodies produces a marked decrease in blood platelets and a risk of serious bleeding. Understanding of the cellular mechanisms that drive drug-induced thrombocytopenia has advanced recently but there is still a need for improved laboratory tests and treatment options. This article provides an overview of the different types of drug-induced thrombocytopenia, discusses potential pathologic mechanisms, and considers diagnostic methods and treatment options. Copyright © 2013 Elsevier Inc. All rights reserved.

Citation

Beng H Chong, Philip Young-Ill Choi, Levon Khachigian, Jose Perdomo. Drug-induced immune thrombocytopenia. Hematology/oncology clinics of North America. 2013 Jun;27(3):521-40

PMID: 23714310

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