Extremely high prevalence of multi-resistance among uropathogens from hospitalised children in Beira, Mozambique.

Birgitta Theodora van der Meeren, Kajal D Chhaganlal, Annett Pfeiffer, Ermelinda Gomez, Josefo J Ferro, Mirrian Hilbink, Cesar Macome, Francien J van der Vondervoort, Konrad Steidel, Peter C Wever

Universidade Católica de Moçambique, Beira, Mozambique. gittavdmeeren@hotmail.com

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2013 Jun

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A prospective surveillance study was conducted to investigate the epidemiology and patterns of antibiotic resistance among uropathogens from hospitalised children in Beira, Mozambique. Additionally, information regarding determinants of a urinary tract infection (UTI) was obtained. Bacterial species identification, antimicrobial susceptibility testing and extended-spectrum beta-lactamase testing were performed for relevant bacterial isolates. Analysis of 170 urine samples from 148 children yielded 34 bacterial isolates, predominantly Escherichia coli and Klebsiella spp., causative of a urinary tract infection in 29 children; 30/34 isolates (88.2%) from 26/29 children (89.7%) were considered highly resistant micro-organisms (HRMOs). No significant determinants of urinary tract infection with HRMOs were detected when analysing gender, antibiotic use during hospital admission and HIV status. This study shows, for the first time in Mozambique, an extremely high prevalence of HRMOs among uropathogens from hospitalised children with a urinary tract infection.

Citation

Birgitta Theodora van der Meeren, Kajal D Chhaganlal, Annett Pfeiffer, Ermelinda Gomez, Josefo J Ferro, Mirrian Hilbink, Cesar Macome, Francien J van der Vondervoort, Konrad Steidel, Peter C Wever. Extremely high prevalence of multi-resistance among uropathogens from hospitalised children in Beira, Mozambique. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 2013 Jun;103(6):382-6