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A general approach for preparing enzyme-polymer nanoconjugates that respond to temperature in organic media is presented. These nanoconjugates readily dissolve in organic solvents for homogenous catalysis at 40 °C and showed greatly enhanced apparent catalytic activities. The recovery of the soluble enzyme-polymer nanoconjugates is accomplished by temperature-induced precipitation.


Jingying Zhu, Yifei Zhang, Diannan Lu, Richard N Zare, Jun Ge, Zheng Liu. Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media. Chemical communications (Cambridge, England). 2013 Jul 11;49(54):6090-2

PMID: 23727906

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