Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Multidrug resistance is a major obstacle to successful chemotherapy of cancer. To overcome multidrug resistance, our research is to develop new liposome and nanomicelle delivery systems. Investigations are focusing on certain aspects, including resistant cancer cell membranes, cancer stem cells, mitochondria, apoptosis genes, vasculogenic mimicry and heterogeneity of cancer cells. Evaluations have been performed on cancer cells, cancer spheroids and cancer animal models. These nanoscale formulations demonstrated an enhanced chemotherapy efficacy in resistant cancer and cancer stem cells in vitro and in vivo.


Rui-Jun Ju, Li-Min Mu, Wan-Liang Lu. Targeting drug delivery systems for circumventing multidrug resistance of cancers. Therapeutic delivery. 2013 Jun;4(6):667-71

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 23738665

View Full Text