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JMML patient-derived iPSCs induce new hypotheses.
Rebecca J Chan, Mervin C Yoder
Blood 2013 Jun 13
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In this issue of Blood, Gandre-Babbe et al have, in part, overcome the obstacle of validating the molecular underpinnings of juvenile myelomonocytic leukemia (JMML) with the generation of induced pluripotent stem cells (iPSCs) from individuals with JMML.
Citation
Rebecca J Chan, Mervin C Yoder.
JMML patient-derived iPSCs induce new hypotheses.
Blood.
2013 Jun 13;121(24):4815-7
Mesh Tags
Female
Humans
Induced Pluripotent Stem Cells
Leukemia, Myelomonocytic, Juvenile
Male
Mutation, Missense
Neoplastic Stem Cells
Protein Tyrosine Phosphatase, Non-Receptor Type 1
Substances
PTPN1 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 1
PMID: 23766458
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