A concise synthesis of xestospongic acid methyl ester with pancreatic lipase inhibitory activity.

Jing-Xu Gong, He-Yao Wang, Wen-Fei He, Zhen-Zhong Wang, Wei Xiao, Yue-Wei Guo

a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai , 201203 , China.

Journal of Asian natural products research 2013 Aug

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Xestospongic acid methyl ester, a naturally brominated fatty acid with potent pancreatic lipase inhibitory activity in vitro, was synthesized from 5-hexynol in 30% total yield.

Citation

Jing-Xu Gong, He-Yao Wang, Wen-Fei He, Zhen-Zhong Wang, Wei Xiao, Yue-Wei Guo. A concise synthesis of xestospongic acid methyl ester with pancreatic lipase inhibitory activity. Journal of Asian natural products research. 2013 Aug;15(8):916-9

PMID: 23796323

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