Dexmedetomidine: new opportunities in anesthesiology].

A S Kulikov, A Yu Lubnin

Anesteziologiia i reanimatologiia 2013 Jan-Feb

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Dexmedetomidine is a novel a,-agonist with unique characteristics. The review contains description of main pharmacological and physiological features of this drug. The experience of off-label using of dexmedetomidine in anesthesia is discussed in details. Authors consider that dexmedetomidine can improve anesthesia management in various clinical situations due to specific sedation profile similar to natural human sleep pattern. It can be helpful in neurosurgery in overweight patients or in patients with high cardiac risk as well as in pediatric practice.