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The use of hydroxamic acids and sodium nitrate to enhance the antitumor effect of cyclophosphamide].
T N Bogatyrenko, Z V Kuropteva, T E Sashenkova, L M Baĭder, N P Konovalova
Voprosy onkologii 2013Sizes of these terms reflect their relevance to your search.
It has been showed that the introduction of nitrocompounds (as nitic oxide donors) in to the compositions of cyclophosphamide and hydroxamic acids for curing animals having leukemia P-388 increased duration of life by 290%. Thereby 40% of animals have recovered. The therapeutic dose cyclophosphamide have been reduced by 6 times.
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T N Bogatyrenko, Z V Kuropteva, T E Sashenkova, L M Baĭder, N P Konovalova. The use of hydroxamic acids and sodium nitrate to enhance the antitumor effect of cyclophosphamide]. Voprosy onkologii. 2013;59(1):94-8
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PMID: 23814833
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