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Stannous fluoride has a long history of use in the improvement of oral health, and was the fluoride source first proven to provide anti-caries benefits when delivered from a dentrifrice formulation. This paper provides an account of the early use of stannous fluoride, primarily for an anti-caries benefit, and the subsequent attempts to formulate stannous fluoride into stable formulations where additional benefits of the stannous cation can be realized.

Citation

Stephen A Makin. Stannous fluoride dentifrices. American journal of dentistry. 2013 Mar;26 Spec No A:3A-9A

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PMID: 23833912

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