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Protection of 2'-hydroxyls in the chemical synthesis of oligoribonucleotides].

A V Aralov, O G Chakhmakhchieva

Bioorganicheskaia khimiia 2013 Jan-Feb


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  • ethers (2)
  • hydroxyl radical (2)
  • molecular structure (1)
  • nucleotide (1)
  • oligoribonucleotides (4)
  • rna (3)
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    The review is devoted to the chemical synthesis of oligoribonucleotides and the protecting groups used. In particular the existent methods of blocking 2'-OH function in nucleotide monomers for the RNA synthesis are discussed in detail.

    Citation

    A V Aralov, O G Chakhmakhchieva. Protection of 2'-hydroxyls in the chemical synthesis of oligoribonucleotides]. Bioorganicheskaia khimiia. 2013 Jan-Feb;39(1):3-25

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    PMID: 23844504

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