Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

To develop a quality analysis method based on self-reference principal for dissolution determination of Shuanghuanglian capsules. Dissolution of Shuanghuanglian capsules was determined by principal component analysis consociated HPLC method. The liner of regression equation was good. The average recovery rates of quality assurance samples (QA) and quality control samples (QC) were all no less than 96. 0%. Dissolution curves of Shuanghuanlian capsules of different manufacturers and different batches of the same manufacturer had obvious disparity. The method can better evaluate the dissolution conditions of Shuanghuanglian capsules. The prospect of the method is expected for assessing the dissolution of other oral solid dosage of traditional Chinese medicines.


Wei-Quan Zhang, Huai-Zhong Guo, Xiao-Qian Zhang, Qian-Yi Liu. Dissolution determination of Shuanghuanglian capsules by HPLC analysis assisted with principal component analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2013 Apr;38(7):985-9

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 23847942

View Full Text