A case of a giant rectal gastrointestinal stromal tumor radically resectable after treatment with neoadjuvant imatinib mesylate].

Motoki Sassa, Yusuke Kobayashi, Hidekazu Sugeno, Manabu Iwadate, Satoshi Suzuki, Yoshiyuki Endo, Izumi Nakamura, Shinji Ohki, Seiichi Takenoshita

Dept. of Organ Regulatory Surgery, Fukushima Medical University.

Gan to kagaku ryoho. Cancer & chemotherapy 2013 Jul

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A 64-year-old male patient was diagnosed with rectal gastrointestinal stromal tumor(GIST)by prostate biopsy, because of high PSA. We considered that a radical operation was impossible because the tumor occupied the pelvis, and we suspected prostate invasion. After neoadjuvant chemotherapy(imatinib mesylate 400 mg/day), the tumor size was reduced(90×85 mm→60×50mm), and we could thus perform radical resection. The patient is currently receiving adjuvant chemotherapy (imatinib mesylate 400 mg/day), without recurrence.

Citation

Motoki Sassa, Yusuke Kobayashi, Hidekazu Sugeno, Manabu Iwadate, Satoshi Suzuki, Yoshiyuki Endo, Izumi Nakamura, Shinji Ohki, Seiichi Takenoshita. A case of a giant rectal gastrointestinal stromal tumor radically resectable after treatment with neoadjuvant imatinib mesylate]. Gan to kagaku ryoho. Cancer & chemotherapy. 2013 Jul;40(7):937-41