The cardiology and endocrinology connection between amiodarone and thyrotoxicosis: case report and review of the literature.

Amiodarone is used in a large number of cardiac conditions. Amiodarone-induced thyroid dysfunction has been reported to affect up to 20% of users. Amiodarone can lead to both amiodarone-induced hypothyroidism (AIH) and less commonly amiodarone-induced thyrotoxicosis (AIT). There are two main forms of AIT. Type 1 AIT, a form of io-dine-induced hyperthyroidism, and type 2, a drug-induced destructive thyroiditis. Type 1 AIT develops on individuals with underlying thyroid disease. Treatment of Type 1 AIT includes the use of antithyroid drugs and discontinuation of amiodarone. Type 2 AIT is commonly self-limiting in nature. In this article wedescribe a patient with Amiodarone-induced thyrotoxicosis discussing its clinical features and medical therapeutic approach.

Citation

Coromoto Palermo-Garófalo, José Hernán Martínez, Frieda Silva, Eva González, Oberto Torres, Jannette Figueroa, José González, Miranda María de Lourdes. The cardiology and endocrinology connection between amiodarone and thyrotoxicosis: case report and review of the literature. Boletín de la Asociación Médica de Puerto Rico. 2013;105(2):47-53

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PMID: 23882990

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