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This review of literature describes a role of chronic stress in the development of substance dependence including alcohol dependence. It is focused on neurochemical mechanisms of this dependence and approaches to its treatment in people with mental adaptation disorders. An example of treatment with injectable extended-release naltrexone is presented.

Citation

T V Agibalova, O V Rychkova, A G Kuznetsov, G L Gurevich, D S Val'chuk, A D Petrov. Alcohol dependence and mental adaptation disorders (the use of injectable extended-release naltrexone)]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov. 2013;113(6 Pt 2):63-8

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PMID: 23887471

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