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    The optimal route (oral versus intravenous) of antibiotic administration for pediatric acute osteomyelitis is not well established. Seventy-eight children from our university hospital and 17 children at our county hospital were treated for acute osteomyelitis. The rates of intravenous antibiotics upon discharge were 95% versus 65% (P=0.002), respectively. The recurrence rate and line complication rates were 10% and 24% at the university hospital, compared to 0% (P=0.34) and 6% (P=0.29) at the county hospital. Based on this data, a prospective comparison between intravenous and early oral antibiotic therapy for pediatric acute osteomyelitis is recommended.


    Raymond W Liu, Hadeel Abaza, Priyesh Mehta, Jennifer Bauer, Daniel R Cooperman, Allison Gilmore. Intravenous versus oral outpatient antibiotic therapy for pediatric acute osteomyelitis. The Iowa orthopaedic journal. 2013;33:208-12

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    PMID: 24027485

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