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Humanized NOD-SCID IL2rg–/– mice as a preclinical model for cancer research and its potential use for individualized cancer therapies.
Qianjun Zhou, John Facciponte, Min Jin, Qiang Shen, Qiang Lin
Cancer letters 2014 Mar 1Sizes of these terms reflect their relevance to your search.
Humanized mouse models have been developed and utilized in cancer research for decades. Newly developed combined immunodeficient NOD-SCID-IL2rg–/– mice are more permissive for human cells and tissue engraftment. In this review, we discuss the use of NOD-SCID-IL2rg(–/–) mice as a preclinical tool in cancer research and its potential use for individualized cancer therapies.
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Qianjun Zhou, John Facciponte, Min Jin, Qiang Shen, Qiang Lin. Humanized NOD-SCID IL2rg–/– mice as a preclinical model for cancer research and its potential use for individualized cancer therapies. Cancer letters. 2014 Mar 1;344(1):13-9
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PMID: 24513265
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