Achilles tendinopathy following Kaletra (lopinavir/ritonavir) use.

F V Cresswell, J Tomlins, D R Churchill, K Walker-Bone, D Richardson

International journal of STD & AIDS 2014 Oct

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A multitude of rheumatologic manifestations have been associated with HIV infection and protease inhibitors use. We describe two cases that display a temporal relationship between initiating Kaletra and developing Achilles tendinopathy. Immediate and dramatic resolution of symptoms occurred on switching from Kaletra to an alternative agent. Clinicians may want to consider a trial of an alternative agent in individuals on Kaletra who experience Achilles tendinopathy. Adverse events must be formally reported so that our understanding of antiretrovirals may continually evolve and aid decisions about antiretroviral prescribing. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Citation

F V Cresswell, J Tomlins, D R Churchill, K Walker-Bone, D Richardson. Achilles tendinopathy following Kaletra (lopinavir/ritonavir) use. International journal of STD & AIDS. 2014 Oct;25(11):833-5