Pons herniation into skull base after cabergoline therapy of giant prolactinoma.

Jesús Moles Herbera, David Rivero Celada, Inmaculada Montejo Gañan, David Fustero de Miguel, Carlos Fuentes Uliaque, Ana Carmen Vela Marín

Pituitary 2015 Feb

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Pons herniation after cabergoline therapy for giant prolactinoma is a complication not documented in literature. We report a medium aged patient who developed secondary hemiparesis after 18 months of medical treatment. MRI revealed pons herniation into the clivus. There was improvement with conservative treatment. Secuencial MRIs are presented showing the tumor at the moment of the diagnosis, tumor shrinkage and pons herniation. Some studies have shown that a significant and rapid tumor shrinkage resulting from treatment with cabergoline can occur and it is thought that some complications are related with this tumor regression, as in the presented case.

Citation

Jesús Moles Herbera, David Rivero Celada, Inmaculada Montejo Gañan, David Fustero de Miguel, Carlos Fuentes Uliaque, Ana Carmen Vela Marín. Pons herniation into skull base after cabergoline therapy of giant prolactinoma. Pituitary. 2015 Feb;18(1):68-71