Anna Borioni, Gianluca Gostoli, Elena Bossù, Isabella Sestili
Journal of pharmaceutical and biomedical analysis 2014 JunNuclear magnetic resonance spectroscopy was used for direct quantitative determination of iobitridol in an injectable formulation. The method was developed on a medium field strength magnet (400MHz) and validation was performed by assessing specificity, accuracy, precision, linearity, stability of samples and robustness. Validation data confirm that the method is highly appropriate for direct quantification of iobitridol in the final formulation. Moreover the method has a good potential for rapid screening analyses due to straightforward experimental setup and lack of any sample pretreatment. Copyright © 2014 Elsevier B.V. All rights reserved.
Anna Borioni, Gianluca Gostoli, Elena Bossù, Isabella Sestili. Quantitative analysis of iobitridol in an injectable preparation by 1H NMR spectroscopy. Journal of pharmaceutical and biomedical analysis. 2014 Jun;94:19-22
PMID: 24531005
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