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A recent study demonstrates a new mechanism by which crosstalk between multiple guidance cues is integrated during axon pathfinding. FLRT3 is a novel co-receptor for Robo1 that acts as a context-dependent modulator of Netrin-1 attraction in thalamocortical axons. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Laura Anne Lowery. Axon guidance: FLRTing promotes attraction. Current biology : CB. 2014 Mar 03;24(5):R198-200
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PMID: 24602885
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