Calcein-modified multiporous films with conical channels are introduced in a nanofluid device to enhance the calcium-responsive intensity and stability of ionic currents. Calcein with more carboxyls enhances the response of channels to calcium ions, and the capability of immobilized calcein for Ca(2+)-binding could be regulated by the deprotonation of these carboxyls.
Zheyi Meng, Chendi Jiang, Xiulin Li, Jin Zhai. Calcein-modified multinanochannels on PET films for calcium-responsive nanogating. ACS applied materials & interfaces. 2014 Mar 26;6(6):3794-8
PMID: 24625352
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