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Hsp90 picks PIKKs via R2TP and Tel2.
Cara K Vaughan
Structure (London, England : 1993) 2014 Jun 10
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Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90. Copyright © 2014 Elsevier Ltd. All rights reserved.
Citation
Cara K Vaughan.
Hsp90 picks PIKKs via R2TP and Tel2.
Structure (London, England : 1993).
2014 Jun 10;22(6):799-800
Mesh Tags
HSP90 Heat-Shock Proteins
Nuclear Proteins
Saccharomyces cerevisiae Proteins
Telomere-Binding Proteins
Substances
HSP82 protein, S cerevisiae
HSP90 Heat-Shock Proteins
Nuclear Proteins
PIH1 protein, S cerevisiae
Saccharomyces cerevisiae Proteins
Tel2 protein, S cerevisiae
Telomere-Binding Proteins
PMID: 24918336
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