Association between aggregative adherence fimbriae types including putative new variants and virulence-related genes and clump formation among aggR-positive Escherichia coli strains isolated in Thailand and Japan.

Microbiology and immunology 2014 Aug

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Enteroaggregative Escherichia coli (EAggEC) are an important cause of diarrhea. Four types of AAF have been identified; however, their prevalence and association with virulence properties remain unclear. E. coli strains carrying the aggR gene as EAggEC that were isolated in Japan and Thailand (n = 90) were examined for AAF subunit genes, two toxin genes (pet/astA), and clump formation. The most prevalent AAF gene was hdaA (28%), followed by aafA (20%), aggA (12%), and agg3A (4%), as well as a putative new AAF sequence (25.6%). Retention status of the toxin genes and intensities of clump formation appeared to vary according to the AAF type. © 2014 The Societies and Wiley Publishing Asia Pty Ltd.

Citation

Kenitiro Ito, Shigeru Matsushita, Mitsugu Yamazaki, Kazuo Moriya, Takayuki Kurazono, Noriaki Hiruta, Hiroshi Narimatsu, Nobuhiro Ueno, Junko Isobe, Jun Yatsuyanagi, Norimichi Kumagai, Michiko Hashimoto, Orn-Anong Ratchtrachenchai. Association between aggregative adherence fimbriae types including putative new variants and virulence-related genes and clump formation among aggR-positive Escherichia coli strains isolated in Thailand and Japan. Microbiology and immunology. 2014 Aug;58(8):467-73