Predictive factors for a single successful cytapheresis session during the first mobilisation.

A C Gac, J J Parienti, S Chantepie, S Cheze, H Johnson-Ansah, K Benabed, M Macro, V Lefevre, A Batho, C Fruchart, O Reman

Leukemia research 2014 Sep

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To avoid repeated apheresis, the objective of this study was to analyse the predictive factors for a single successful cytapheresis during the first mobilisation. The pre-collection characteristics of 170 lymphoma and 95 myeloma patients were analysed. Among 60 lymphoma patients who had less than 30 CD34 cells/mm(3) the day before the first apheresis, an increase in the CD34 cell count between Day -1 and Day 1 was predictive of first stem cell mobilisation success, with a sensitivity of 100% if the Day 1 was higher than 30/mm(3) (10/60 patients). Success rate of obtaining an appropriate number of stem cells in one apheresis was 120 among 170 patients. Copyright © 2014 Elsevier Ltd. All rights reserved.

Citation

A C Gac, J J Parienti, S Chantepie, S Cheze, H Johnson-Ansah, K Benabed, M Macro, V Lefevre, A Batho, C Fruchart, O Reman. Predictive factors for a single successful cytapheresis session during the first mobilisation. Leukemia research. 2014 Sep;38(9):1020-4