Sihem Mahrouki, Hela Chihi, Amel Bourouis, Khaoula Ayari, Mustapha Ferjani, Mohamed Ben Moussa, Omrane Belhadj
Diagnostic microbiology and infectious disease 2015 JanThe aim of this study is to report the emergence of IncA/C conjugative plasmids harboring blaTEM-24, blaDHA-1, qnrA6, and aac(6')-Ib-cr genes among Providencia spp. isolates recovered in 2008 in Tunisia. The double-disk synergy test confirmed the phenotype extended-spectrum β-lactamase (ESBL) in 2 Providencia stuartii and 5 Providencia rettgeri. These ESBLs were coresistant to cefoxitin, chloramphenicol, ofloxacin, and sulfonamides but remained susceptible to imipenem. Three β-lactamases TEM-2, TEM-24, and DHA-1 were detected. blaTEM-24, blaDHA-1, aac(6')-Ib-cr, and qnrA6 genes were successfully transferred to Escherichia coli strain HB101, and they were found located on the conjugatifs IncA/C plasmids. Genetic relatedness showed similar and different patterns among P. stuartii and P. rettgeri strains, respectively. Copyright © 2015 Elsevier Inc. All rights reserved.
Sihem Mahrouki, Hela Chihi, Amel Bourouis, Khaoula Ayari, Mustapha Ferjani, Mohamed Ben Moussa, Omrane Belhadj. Nosocomial dissemination of plasmids carrying blaTEM-24, blaDHA-1, aac(6')-Ib-cr, and qnrA6 in Providencia spp. strains isolated from a Tunisian hospital. Diagnostic microbiology and infectious disease. 2015 Jan;81(1):50-2
PMID: 25315769
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