Concise cascade reactions of pyruvates with aldehydes that generate functionalized dihydropyran derivatives in one pot have been developed. The products, dihydropyrans, were further concisely transformed to various molecules.
Pandurang V Chouthaiwale, Fujie Tanaka. Reactions of pyruvates: organocatalytic synthesis of functionalized dihydropyrans in one pot and further transformations to functionalized carbocycles and heterocycles. Chemical communications (Cambridge, England). 2014 Dec 7;50(94):14881-4
PMID: 25325901
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