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Tuning the selectivity of triplex DNA receptors.
Haidong Huang, Peter C Tlatelpa
Chemical communications (Cambridge, England) 2015 Mar 28
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Effects of hydrogen bonding clamps on the selectivity of triplex DNA receptors were studied. Incorporation of a 5-methyl-2-thiocytosine base to the parallel homopyrimidine region of a triplex receptor enabled selective molecular recognition of an inosine ligand.
Citation
Haidong Huang, Peter C Tlatelpa.
Tuning the selectivity of triplex DNA receptors.
Chemical communications (Cambridge, England).
2015 Mar 28;51(25):5337-9
Mesh Tags
Cytosine
DNA
Hydrogen Bonding
Inosine
Ligands
Models, Molecular
Molecular Conformation
Pyrimidines
Receptors, Cell Surface
Substances
DNA receptor
Ligands
Pyrimidines
Receptors, Cell Surface
triplex DNA
2-thiocytosine
Inosine
Cytosine
DNA
pyrimidine
PMID: 25358435
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