Effects of hydrogen bonding clamps on the selectivity of triplex DNA receptors were studied. Incorporation of a 5-methyl-2-thiocytosine base to the parallel homopyrimidine region of a triplex receptor enabled selective molecular recognition of an inosine ligand.
Haidong Huang, Peter C Tlatelpa. Tuning the selectivity of triplex DNA receptors. Chemical communications (Cambridge, England). 2015 Mar 28;51(25):5337-9
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PMID: 25358435
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