Iron- and cobalt-catalyzed arylation of azetidines, pyrrolidines, and piperidines with Grignard reagents.

Baptiste Barré, Laurine Gonnard, Rémy Campagne, Sébastien Reymond, Julien Marin, Paola Ciapetti, Marie Brellier, Amandine Guérinot, Janine Cossy

Organic letters 2014 Dec 5

filter terms:

Iron- and cobalt-catalyzed cross-couplings between iodo-azetidines, -pyrrolidines, -piperidines, and Grignard reagents are disclosed. The reaction is efficient, cheap, chemoselective and tolerates a large variety of (hetero)aryl Grignard reagents.

Citation

Baptiste Barré, Laurine Gonnard, Rémy Campagne, Sébastien Reymond, Julien Marin, Paola Ciapetti, Marie Brellier, Amandine Guérinot, Janine Cossy. Iron- and cobalt-catalyzed arylation of azetidines, pyrrolidines, and piperidines with Grignard reagents. Organic letters. 2014 Dec 5;16(23):6160-3